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Floxuridine

 

Floxuridine

 

Product name  2¢-Deoxy-5-fluorouridine;

1-(2-deoxy-β-D-ribofuranosyl)-5-fluorouracil;  5-fluoro-2’-deoxy-β-uridine

Structure

Molecular Formula          C9H11FN2O5

Molecular Weight             246.20  

CAS Number                  50-91-9

NMPA approval No.     H20059368

National Drug standards     YBH37022005 

Test

USP

Results

Color & Appearance

white crystalline powder

white crystalline powder

Infrared  spectrum

consistent with the structure

Conforms

Melting range

between 145℃ and 153℃, but the range between beginning and end of melting does not exceed 2℃.

149℃~149℃

Specific rotation

between +360 and +390

+380

Loss on Drying

NMT  0.2 % ( 60℃ )

0.1 %

Residue on ignition

NMT  0.1 %

0.05 %

Limit of fluoride ion

7.0 %~8.2 %

7.6 %

Heavy metals (as Pb)

NMT 10 ppm

NMT 10 ppm

Assay ( UV )

98.5%~101.0%

99.8 %

 

Package: 1 kg

Storage:Preserve in tight, light-resistant containers. Store at 25℃.

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